{"product_id":"botulinum-neuroprotein-deep-mechanisms-of-action-and-clinical-consequences","title":"Botulinum Neuroprotein: Deep Mechanisms of Action and Clinical Consequences","description":"\u003cdiv class=\"dentico-course-sheet\" dir=\"ltr\" lang=\"en\"\u003e \u003ch2\u003eBotulinum Neuroprotein: Deep Mechanisms of Action and Clinical Consequences\u003c\/h2\u003e \u003cdiv class=\"dentico-course-meta\"\u003e \u003cp\u003e\u003cstrong\u003eCategory:\u003c\/strong\u003e Aesthetic Medicine\u003c\/p\u003e \u003cp\u003e\u003cstrong\u003eInstructor(s):\u003c\/strong\u003e Sergey Shelehov\u003c\/p\u003e \u003cp\u003e\u003cstrong\u003eCourse structure:\u003c\/strong\u003e Lessons: 3 lessons | Duration: 49 min\u003c\/p\u003e \u003c\/div\u003e \u003ch3\u003eCourse overview\u003c\/h3\u003e \u003cdiv class=\"dentico-course-overview\"\u003e \u003cp\u003eAn exclusive look at the molecular mechanisms of botulinum neuroprotein by \u003cstrong\u003eSergey Yuryevich Shelehov\u003c\/strong\u003e, Candidate of Medical Sciences, neurologist and dermatocosmetologist of the highest category with 26 years of experience in botulinum therapy.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eUnderstanding mechanisms that few discuss, and full control over the clinical outcome — \u003cstrong\u003eall this in one proprietary course\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDuring the course you will study:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003eThe structure of the botulinum neuroprotein molecule and the role of the light and heavy chains\u003cbr\u003eThe mechanism of blockade of acetylcholine release and damage to the SNARE complex\u003cbr\u003eReasons for rapid and delayed onset of effect\u003cbr\u003eSelection of optimal dosing and injection techniques for different facial zones\u003cbr\u003eClinical strategies to reduce the risk of adverse effects\u003cbr\u003eProtocols for predicting aesthetic outcomes\u003cbr\u003eAnalysis of errors and review of complex clinical cases.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eAfter the course you will understand the molecular mechanisms of botulinum toxin action, predict the clinical effect and minimize the risks of reduced therapy effectiveness.\u003c\/p\u003e \u003c\/div\u003e \u003ch3\u003eCourse lessons\u003c\/h3\u003e \u003cdiv class=\"dentico-lesson-list\"\u003e \u003cdiv class=\"dentico-lesson-card\"\u003e \u003ch4 class=\"dentico-lesson-heading\"\u003e \u003cspan class=\"dentico-lesson-number\"\u003eLesson 1.\u003c\/span\u003e \u003cspan class=\"dentico-lesson-name\"\u003eThe Botulinum Neuroprotein Molecule and Basics of the Mechanism of Action\u003c\/span\u003e \u003c\/h4\u003e \u003cdiv class=\"dentico-lesson-program\"\u003e\n\u003cp\u003eThe history of botulinum neuroprotein use in medicine\u003cbr\u003eThe structure of the molecule.\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003eThe role of the transport protein complex:\u003cbr\u003e \u003c\/p\u003e\n\u003cp\u003ePenetration of the neuroprotein into the nerve terminal\u003c\/p\u003e\n\u003cp\u003eThe mechanism of blockade of acetylcholine release.\u003cbr\u003e \u003c\/p\u003e\n\u003cp\u003eStages of botulinum neuroprotein (BNP) action \u003cbr\u003ePhysiology of the nervous system interaction with targets\u003cbr\u003eDamage to the SNARE complex.\u003cbr\u003e \u003c\/p\u003e\n\u003cp\u003eDisruption of synaptic transmission:\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003eWhy botulinum toxin works selectively and locally\u003cbr\u003eBiological prerequisites of the clinical effect.\u003c\/p\u003e\n\u003c\/div\u003e \u003c\/div\u003e \u003cdiv class=\"dentico-lesson-card\"\u003e \u003ch4 class=\"dentico-lesson-heading\"\u003e \u003cspan class=\"dentico-lesson-number\"\u003eLesson 2.\u003c\/span\u003e \u003cspan class=\"dentico-lesson-name\"\u003eDynamics of Effect: From Injection to Clinical Result\u003c\/span\u003e \u003c\/h4\u003e \u003cdiv class=\"dentico-lesson-program\"\u003e\n\u003cp\u003eStages of clinical effect development after administration\u003cbr\u003eRapid onset of action: possible mechanisms\u003cbr\u003eEarly paradoxical reactions\u003cbr\u003ePharmacokinetics and pharmacodynamics of BNP behavior.\u003cbr\u003e \u003c\/p\u003e\n\u003cp\u003eFeatures of interaction with the nerve terminal:\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003eDelayed effects and their biological rationale\u003cbr\u003eResynthesis of the SNARE complex and restoration of impulse transmission\u003cbr\u003eDose-dependence and influence of concentration\u003cbr\u003eDiffusion of the drug and factors affecting spread.\u003c\/p\u003e\n\u003c\/div\u003e \u003c\/div\u003e \u003cdiv class=\"dentico-lesson-card\"\u003e \u003ch4 class=\"dentico-lesson-heading\"\u003e \u003cspan class=\"dentico-lesson-number\"\u003eLesson 3.\u003c\/span\u003e \u003cspan class=\"dentico-lesson-name\"\u003eIndividual Sensitivity and Secondary Inefficacy\u003c\/span\u003e \u003c\/h4\u003e \u003cdiv class=\"dentico-lesson-program\"\u003e\n\u003cp\u003eIndividual variability of response to botulinum toxin\u003cbr\u003eCauses of primary inefficacy\u003cbr\u003eSecondary inefficacy\u003cbr\u003eDistant effects of BNP action\u003cbr\u003eInteractions with medicinal products\u003cbr\u003eFormation of neutralizing antibodies.\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003eImmunogenicity of different preparations:\u003cbr\u003e \u003c\/p\u003e\n\u003cp\u003eRisk factors for reduced therapy effectiveness\u003cbr\u003eErrors in interpretation of the clinical result\u003cbr\u003ePractical conclusions for safe and predictable practice.\u003c\/p\u003e\n\u003c\/div\u003e \u003c\/div\u003e \u003c\/div\u003e \u003c\/div\u003e","brand":"دينتيكو لكورسات طب الاسنان","offers":[{"title":"Default Title","offer_id":57626014384508,"sku":"DENTICO-Q424Y4WAXSKQ","price":20.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0919\/1446\/9756\/files\/130dd315.webp?v=1791568783","url":"https:\/\/dentalcourse.store\/products\/botulinum-neuroprotein-deep-mechanisms-of-action-and-clinical-consequences","provider":"Dentico || لكورسات طب الاسنان","version":"1.0","type":"link"}